Found 18 matching trials
Addition of Belimumab to B-cell Depletion in Relapsing-remitting Multiple Sclerosis PHASE2 Multiple sclerosis is the most common inflammatory disease of the central n...
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Johns Hopkins University
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A Study to Assess Bioequivalence of Two Subcutaneous (SC) Formulations of Ocrelizumab in Participants With Multiple Sclerosis (MS) PHASE2 The main purpose of this study is to assess the bioequivalence of ocrelizum...
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Active Not Recruiting
Location
Profound Research, LLC
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A Study to Investigate the Safety, Tolerability, Pharmacokinetics, Immunogenicity, and Pharmacodynamics of a New Subcutaneous Formulation of Ocrelizumab in Participants With Multiple Sclerosis PHASE1 The main purpose of this study is to evaluate the safety and tolerability o...
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Active Not Recruiting
Location
Profound Research, LLC
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Multiple Sclerosis Patient Experience on Kesimpta and Ocrevus Subcutaneous Formulation N/A The study aims to compare the experiences, including injection-related reac...
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Novartis Investigative site
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A Study of Ocrelizumab Administered Subcutaneously in Participants With Multiple Sclerosis Who Switch From an Approved Anti-CD20 Therapy PHASE4 The purpose of this study is to assess the imaging biomarkers, patient outc...
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Caribbean Center for Clinical Research
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Traditional Versus Early Aggressive Therapy for Multiple Sclerosis Trial NA FDA-approved multiple sclerosis (MS) disease-modifying therapies (DMTs) tar...
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Active Not Recruiting
Location
University of Alabama at Birmingham
Treatments Being Tested
Natalizumab/natalizumab-sztn, Alemtuzumab, Ocrelizumab, Rituximab/rituximab-arrx/rituximab-abbs/rituximab-pvvr, Cladribine, Ofatumumab, Ublituximab-xiiy, Ocrelizumab and hyaluronidase-ocsq Glatiramer acetate, Interferons (intramuscular, subcutaneous, pegylated) Teriflunomide, Fumarates (dimethyl, diroximel, monomethyl) Fingolimod, Siponimod, Ozanimod, Ponesimod Learn More & Join Trial
Randomized Autologous heMatopoietic Stem Cell Transplantation Versus Alemtuzumab, Cladribine or Ocrelizumab for RRMS (RAM-MS) PHASE3 This study is a randomized multicentre, multinational, treatment interventi...
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Active Not Recruiting
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An Extension Study to Assess Impact of Multiple Sclerosis (MS) on Physical Function and Provide Continued Ocrelizumab Treatment PHASE3 The study will evaluate the physical impact of MS from participant's perspe...
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CHU Amiens Hopital Sud
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A Study of Ocrelizumab in Comparison With Interferon Beta-1a (Rebif) in Participants With Relapsing Multiple Sclerosis PHASE3 This randomized, double-blind, double-dummy, parallel-group study will eval...
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21st Century Neurology
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A Study to Investigate Effects of Ocrelizumab Treatment on Neurofilament Light Chain (NfL) Levels and Participant Satisfaction in Participants With Multiple Sclerosis (MS) N/A The main purpose of the study is to evaluate participant satisfaction after...
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Uniklinik RWTH Aachen
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